New Knee Surgery Pain Drug Developed
Corgentech Inc. (CGTK.O: Quote, Profile, Research) said on Wednesday that early results from small Phase II trials of its experimental pain drug show the drug reduced pain in patients who had knee replacement surgery, but was no better than a placebo in those undergoing gall bladder removal.
The knee replacement trial, which enrolled 50 patients, showed a relative difference in pain of 24 percent when the patients first began to walk after surgery, according to Corgentech.
The company also said that on a rating scale of zero to 10, with 10 registering the highest degree of pain, the average pain score for the treated group was 5.4, compared with the placebo group’s average of 7.1.
Corgentech said the preliminary data also showed that the drug, known as 4975, was safe and well tolerated.
The company reported in March that the same drug was no more effective than a placebo in a study of 41 patients with pain caused by surgical repair of a hernia of the groin.
The drug is dripped by syringe into a wound prior to closure. In future trials, Corgentech said it will continue to explore other methods to administer the drug, including direct injection into the relevant tissues.
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